Magnezijev askorbil fosfat u prahu
1. Što je vitaminski fosfat magnezij u prahu ?
Magnezijev askorbil fosfat (MAP), također poznat kao magnezijev askorbil fosfat ili magnezijev VC fosfat, jedan je od derivata vitamina C, sintetiziranih esterizacijom vitamina C. Ne samo da ima istu biološku aktivnost kao vitamin C, već je i stabilniji od vitamina C. Fosfat magnezija vitamina C koji proizvodi Xi'an Youth Biotech sirovina je kozmetičke kvalitete čistoće do 98%, bijeli do svijetložuti prah. Zbog svoje lipofilnosti, magnezijev fosfat vitamina C lako se apsorbira u kožu, topiv je u vodi i razrijeđenoj kiselini, netopljiv u organskim otapalima kao što su eter, etanol, kloroform itd., te ima dobru fototermalnu stabilnost.
2. Osnovne informacije:
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Product Name
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Magnesium ascorbyl phosphate
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Other Name
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Ascorbate phosphate acid magnesium
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CAS
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113170-55-1
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Molecular formula
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C12H12O18P2Mg3.10H2O
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Molecular weight
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759.22
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Appearance
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White crystal powder
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Purity
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99%
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Solubility
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Water solubility
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stability
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Keep it’s color in pH 3.0-6.0 for more than two years
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Mesh
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80-100 Mesh
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Application
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Nutritional supplement; antioxidant preservation agent.
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3. Karakteristike vitamina C fosfata magnezija kao kozmetičkog sastojka:
Otporan na alkalije, otporan na visoke temperature, ne oksidira lako i relativno je stabilan na svjetlu, toplini i zraku. Stupanj oksidacije u kipućoj vodi je samo 1/10 VC;
*Inhibira aktivnost tirozinaze i smanjuje melanin;
*Nakon ulaska u tijelo, može eliminirati slobodne radikale kisika i pospješiti proizvodnju kolagena;
*Stabilan i nije lako promijeniti boju;
*Nije toksičan i ne iritira.
4. Primjena i preporučena doza vitamina C fosfata magnezija:
Magnezijev fosfat vitamina C naširoko se koristi u kozmetici, kao što su krema za oči, esencija, losion, losion, krema za lice, krema za sunčanje, tekući puder i druga kozmetika s različitim teksturama, a također se može napraviti u deterdžentima, kao što su sredstvo za čišćenje očiju, gel za kupanje, pasta za zube itd.
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Specification
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Recommended dosage
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Vitamin C magnesium phosphate 98%
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≤3%
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Mjere predostrožnosti:
*Stabilan u neutralnom pH i ne iritira kožu;
*Obično se koristi u kombinaciji s vitaminom E, ima sinergistički učinak;
Stabilan u otopinama i emulzijama;
Pretjerana uporaba može ometati normalnu enzimsku pretvorbu tirozina u melanin u koži, uzrokujući nelagodu na koži.
5. Trenutačno postoje dvije glavne metode za sintetiziranje magnezijevog fosfata vitamina C u zemlji i inozemstvu: metoda izravne acilacije i metoda grupne zaštite.
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Two Methods
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Direct Acylation Method
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Radical Protection Method
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Step
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Vitamin C phosphate magnesium was synthesized in one step using pyridine, sodium carbonate, and magnesium oxide as catalysts.
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Firstly, VC is converted into 5,6-0 isopropylidene-L ascorbic acid using pyridine and potassium hydroxide as catalysts. After phosphorylation, the protective group is removed through a hydrogen type strong acidic anion exchange resin column, and then converted into magnesium salt.
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Advantage
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The reaction steps are simple and the yield is as high as 86.7%
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The purity of the obtained product is over 96%
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Shortcoming
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The purity of the obtained product is relatively low
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The reaction process is complicated and the yield is relatively low, exceeding 55%.
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6 、 Vitamin C P fosfat M magnezij VS V vitamin C G lukozid：
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Prdouct Name
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Magnesium Ascorbyl Phosphate
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Vitamin C Glucoside
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Relation
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All are derivatives of vitamin C and have higher stability than vitamin C.
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Molecular formula
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C12H12O18P2Mg3·10H2O
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C12H18O11
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ph stability
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High stability at pH around 7
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Stable across a wide pH range
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Mechanism of action
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After entering the human body, magnesium phosphate ester of vitamin C rapidly hydrolyzes and releases vitamin C through phosphatase, thereby inhibiting tyrosinase activity.
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After entering the skin cell body, VC glucoside is converted into vitamin C through enzymatic hydrolysis, which can inhibit the activity of tyrosinase and reduce melanin production.
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Application
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Cosmetic Raw Material
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7. COA:
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Product Name
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Magnesium Ascorbyl Phosphate
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Batch No.
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MAP20211103
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Quantity
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3000 Kg
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Grade
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Cosmetic Grade
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Manufacture Date
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2021-11-03
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Expiry Date
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2023-11-02
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Item
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Specification
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Result
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Appearance
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Free flowing white powder
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Conforms
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Assay (ANHYDROUS) %
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98 min
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99.60
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Loss on drying %
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20.0 max
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12.0
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Heavy metals %
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0.001 max
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Conforms
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Arsenic %:
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0.0002 max
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Conforms
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pH value (3% aqueous solution)
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7.0 - 8.5
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7.8
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Color of solution (APHA)
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70 max
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Conforms
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Free ascorbic acid %
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0.50 max
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0.10
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Specific Rotation
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+21.5º~ +26.5º
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23.9
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Free phosphoric acid %
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1.0 max
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Conforms
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Chloride %
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0.35 max
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Conforms
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Total aerobic count (cfu/g)
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100 max
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Conforms
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Kontaktirajte sada
Youth Biotech CO,. Ltd.